A Major Histocompatibility Class I Locus Contributes to Multiple Sclerosis Susceptibility Independently from HLA-DRB1*15:01

BACKGROUND: In Northern European descended populations, genetic susceptibility for multiple sclerosis (MS) is associated with alleles of the human leukocyte antigen (HLA) Class II gene DRB1. Whether other major histocompatibility complex (MHC) genes contribute to MS susceptibility is controversial....

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Main Authors: Cree, Bruce A. C., Rioux, John D., McCauley, Jacob L., Gourraud, Pierre-Antoine F. D., Goyette, Philippe, McElroy, Joseph, De Jager, Philip, Santaniello, Adam, Vyse, Timothy J., Gregersen, Peter K., Mirel, Daniel, Hafler, David A., Haines, Jonathan L., Pericak-Vance, Margaret A., Compston, Alastair, Sawcer, Stephen J., Oksenberg, Jorge R., Hauser, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892470/
https://ncbi.nlm.nih.gov/pubmed/20593013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011296
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