Effect of age at puberty on risk of multiple sclerosis: A mendelian randomization study

OBJECTIVE: To investigate the potential for a causal effect of age at puberty on multiple sclerosis (MS) susceptibility using a mendelian randomization (MR) approach. METHODS: We used 372 genetic variants strongly associated with age at menarche in a genome-wide association study (GWAS) involving 32...

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Publicat a:Neurology
Autors principals: Harroud, Adil, Morris, John A., Forgetta, Vincenzo, Mitchell, Ruth, Smith, George Davey, Sawcer, Stephen J., Richards, J. Brent
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550505/
https://ncbi.nlm.nih.gov/pubmed/30894442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000007325
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