CIITA variation in the presence of HLA-DRB1*1501 increases risk for multiple sclerosis

The MHC class II transactivator gene (CIITA) is an important transcription factor regulating gene required for HLA class II MHC-restricted antigen presentation. Association with HLA class II variation, particularly HLA-DRB1*1501, has been well-established for multiple sclerosis (MS). In addition, th...

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Autori principali: Bronson, Paola G., Caillier, Stacy, Ramsay, Patricia P., McCauley, Jacob L., Zuvich, Rebecca L., De Jager, Philip L., Rioux, John D., Ivinson, Adrian J., Compston, Alastair, Hafler, David A., Sawcer, Stephen J., Pericak-Vance, Margaret A., Haines, Jonathan L., Hauser, Stephen L., Oksenberg, Jorge R., Barcellos, Lisa F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
Soggetti:
Association Studies Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865376/
https://ncbi.nlm.nih.gov/pubmed/20211854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq101
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