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Allelic variant in CTLA4 alters T cell phosphorylation patterns

Little is known regarding the functional effects of common autoimmune susceptibility variants on human immune cells. The SNP CT60 (rs3087243; A/G) located in the 3′ UTR of the CTLA4 gene has been associated with autoimmune diseases. We examined a cohort of healthy individuals stratified by genotypes...

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Detalles Bibliográficos
Main Authors: Maier, Lisa M., Anderson, David E., De Jager, Philip L., Wicker, Linda S., Hafler, David A.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2141824/
https://ncbi.nlm.nih.gov/pubmed/18000051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706409104
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