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Missense Variants of Uncertain Significance (VUS) Altering the Phosphorylation Patterns of BRCA1 and BRCA2
Mutations in BRCA1 and BRCA2 are responsible for a large proportion of breast-ovarian cancer families. Protein-truncating mutations have been effectively used in the clinical management of familial breast cancer due to their deleterious impact on protein function. However, the majority of missense v...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3660339/ https://ncbi.nlm.nih.gov/pubmed/23704879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062468 |
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