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Functional assays for analysis of variants of uncertain significance in BRCA2
Missense variants in the BRCA2 gene are routinely detected during clinical screening for pathogenic mutations in patients with a family history of breast and ovarian cancer. These subtle changes frequently remain of unknown clinical significance because of the lack of genetic information that may he...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3995136/ https://ncbi.nlm.nih.gov/pubmed/24323938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.22478 |
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