CTLA-4 Genetic Variants Predict Survival in Patients with Sepsis

Cytotoxic T lymphocyte-associated protein 4 (CTLA-4) is a coinhibitory checkpoint protein expressed on the surface of T cells. A recent study by our working group revealed that the rs231775 single nucleotide polymorphism (SNP) in the CTLA-4 gene was associated with the survival of patients with seps...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Mewes, Caspar, Büttner, Benedikt, Hinz, José, Alpert, Ayelet, Popov, Aron-Frederik, Ghadimi, Michael, Beissbarth, Tim, Tzvetkov, Mladen, Jensen, Ole, Runzheimer, Julius, Quintel, Michael, Shen-Orr, Shai, Bergmann, Ingo, Mansur, Ashham
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6352177/
https://ncbi.nlm.nih.gov/pubmed/30634576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8010070
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