Lack of an Association between the Functional Polymorphism TREM-1 rs2234237 and the Clinical Course of Sepsis among Critically Ill Caucasian Patients—A Monocentric Prospective Genetic Association Study

Sepsis is a life-threatening condition and a significant challenge for those working in intensive care, where it remains one of the leading causes of mortality. According to the sepsis-3 definition, sepsis is characterized by dysregulation of the host response to infection. The TREM-1 gene codes for...

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Main Authors: Julius Runzheimer, Caspar Mewes, Benedikt Büttner, José Hinz, Aron-Frederik Popov, Michael Ghadimi, Katalin Kristof, Tim Beissbarth, Joel Schamroth, Mladen Tzvetkov, Bastian Schmack, Michael Quintel, Ingo Bergmann, Ashham Mansur
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-03-01
Colecção:Journal of Clinical Medicine
Assuntos:
90-day mortality
sepsis
single nucleotide polymorphism
survival analysis
TREM-1
Acesso em linha:http://www.mdpi.com/2077-0383/8/3/301
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