TIM-3 Genetic Variants Are Associated with Altered Clinical Outcome and Susceptibility to Gram-Positive Infections in Patients with Sepsis

Background: Previous studies have reported the fundamental role of immunoregulatory proteins in the clinical phenotype and outcome of sepsis. This study investigated two functional single nucleotide polymorphisms (SNPs) of T cell immunoglobulin and mucin domain-containing protein 3 (TIM-3), which ha...

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Pubblicato in:Int J Mol Sci
Autori principali: Mewes, Caspar, Alexander, Tessa, Büttner, Benedikt, Hinz, José, Alpert, Ayelet, Popov, Aron-F., Ghadimi, Michael, Beißbarth, Tim, Tzvetkov, Mladen, Grade, Marian, Quintel, Michael, Bergmann, Ingo, Mansur, Ashham
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7664272/
https://ncbi.nlm.nih.gov/pubmed/33171904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218318
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