Platelet heterogeneity in activation-induced glycoprotein shedding: functional effects

The platelet receptors glycoprotein Ibα (GPIbα) and GPVI are known to be cleaved by members of a disintegrin and metalloprotease (ADAM) family (ADAM10 and ADAM17), but the mechanisms and consequences of this shedding are not well understood. Our results revealed that (1) glycoprotein shedding is con...

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Detaylı Bibliyografya
Yayımlandı:Blood Adv
Asıl Yazarlar: Baaten, Constance C. F. M. J., Swieringa, Frauke, Misztal, Tomasz, Mastenbroek, Tom G., Feijge, Marion A. H., Bock, Paul E., Donners, Marjo M. P. C., Collins, Peter W., Li, Renhao, van der Meijden, Paola E. J., Heemskerk, Johan W. M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2018
Konular:
Thrombosis and Hemostasis
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156892/
https://ncbi.nlm.nih.gov/pubmed/30232085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017011544
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