Platelet heterogeneity in activation-induced glycoprotein shedding: functional effects

The platelet receptors glycoprotein Ibα (GPIbα) and GPVI are known to be cleaved by members of a disintegrin and metalloprotease (ADAM) family (ADAM10 and ADAM17), but the mechanisms and consequences of this shedding are not well understood. Our results revealed that (1) glycoprotein shedding is con...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Blood Adv
Päätekijät: Baaten, Constance C. F. M. J., Swieringa, Frauke, Misztal, Tomasz, Mastenbroek, Tom G., Feijge, Marion A. H., Bock, Paul E., Donners, Marjo M. P. C., Collins, Peter W., Li, Renhao, van der Meijden, Paola E. J., Heemskerk, Johan W. M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2018
Aiheet:
Thrombosis and Hemostasis
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156892/
https://ncbi.nlm.nih.gov/pubmed/30232085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017011544
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