Key role of integrin α(IIb)β(3) signaling to Syk kinase in tissue factor-induced thrombin generation

The fibrin(ogen) receptor, integrin α(IIb)β(3), has a well-established role in platelet spreading, aggregation and clot retraction. How α(IIb)β(3) contributes to platelet-dependent coagulation is less well resolved. Here, we demonstrate that the potent suppressing effect of clinically used α(IIb)β(3...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: van der Meijden, Paola E. J., Feijge, Marion A. H., Swieringa, Frauke, Gilio, Karen, Nergiz-Unal, Reyhan, Hamulyák, Karly, Heemskerk, Johan W. M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: SP Birkhäuser Verlag Basel 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445795/
https://ncbi.nlm.nih.gov/pubmed/22669259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-012-1033-2
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak