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Dual Mechanism of Integrin α(IIb)β(3) Closure in Procoagulant Platelets
Aggregation of platelets via activated integrin α(IIb)β(3) is a prerequisite for thrombus formation. Phosphatidylserine-exposing platelets with a key role in the coagulation process disconnect from a thrombus by integrin inactivation via an unknown mechanism. Here we show that α(IIb)β(3) inactivatio...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3650371/ https://ncbi.nlm.nih.gov/pubmed/23519467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.428359 |
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