Coated platelets function in platelet-dependent fibrin formation via integrin α(IIb)β(3) and transglutaminase factor XIII

Coated platelets, formed by collagen and thrombin activation, have been characterized in different ways: i) by the formation of a protein coat of α-granular proteins; ii) by exposure of procoagulant phosphatidylserine; or iii) by high fibrinogen binding. Yet, their functional role has remained uncle...

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Publicado no:Haematologica
Main Authors: Mattheij, Nadine J.A., Swieringa, Frauke, Mastenbroek, Tom G., Berny-Lang, Michelle A., May, Frauke, Baaten, Constance C.F.M.J., van der Meijden, Paola E.J., Henskens, Yvonne M.C., Beckers, Erik A.M., Suylen, Dennis P.L., Nolte, Marc W., Hackeng, Tilman M., McCarty, Owen J.T., Heemskerk, Johan W.M., Cosemans, Judith M.E.M.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004391/
https://ncbi.nlm.nih.gov/pubmed/26721892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.131441
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