Identification of platelet function defects by multi-parameter assessment of thrombus formation

Assays measuring platelet aggregation (thrombus formation) at arterial shear rate mostly use collagen as only platelet-adhesive surface. Here we report a multi-surface and multi-parameter flow assay to characterize thrombus formation in whole blood from healthy subjects and patients with platelet fu...

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Autors principals: de Witt, Susanne M., Swieringa, Frauke, Cavill, Rachel, Lamers, Moniek M. E., van Kruchten, Roger, Mastenbroek, Tom, Baaten, Constance, Coort, Susan, Pugh, Nicholas, Schulz, Ansgar, Scharrer, Inge, Jurk, Kerstin, Zieger, Barbara, Clemetson, Kenneth J., Farndale, Richard W., Heemskerk, Johan W. M., Cosemans, Judith M.E.M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Pub. Group 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109023/
https://ncbi.nlm.nih.gov/pubmed/25027852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5257
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