Plasminogen associates with phosphatidylserine-exposing platelets and contributes to thrombus lysis under flow

The interaction of plasminogen with platelets and their localization during thrombus formation and fibrinolysis under flow are not defined. Using a novel model of whole blood thrombi, formed under flow, we examine dose-dependent fibrinolysis using fluorescence microscopy. Fibrinolysis was dependent...

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Bibliografske podrobnosti
izdano v:Blood
Main Authors: Whyte, Claire S., Swieringa, Frauke, Mastenbroek, Tom G., Lionikiene, Ausra S., Lancé, Marcus D., van der Meijden, Paola E. J., Heemskerk, Johan W. M., Mutch, Nicola J.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2015
Teme:
Thrombosis and Hemostasis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400293/
https://ncbi.nlm.nih.gov/pubmed/25712989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-09-599480
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