Integrating platelet and coagulation activation in fibrin clot formation

Por Swieringa, Frauke, Spronk, Henri M.H., Heemskerk, Johan W.M., van der Meijden, Paola E.J.
Publicado no Res Pract Thromb Haemost (2018)

Whole Blood Based Multiparameter Assessment of Thrombus Formation in Standard Microfluidic Devices to Proxy In Vivo Haemostasis and Thrombosis

Por Provenzale, Isabella, Brouns, Sanne L. N., van der Meijden, Paola E. J., Swieringa, Frauke, Heemskerk, Johan W. M.
Publicado no Micromachines (Basel) (2019)

Rate-limiting roles of the tenase complex of factors VIII and IX in platelet procoagulant activity and formation of platelet-fibrin thrombi under flow

Por Swieringa, Frauke, Kuijpers, Marijke J. E., Lamers, Moniek M. E., van der Meijden, Paola E. J., Heemskerk, Johan W. M.
Publicado no Haematologica (2015)

Key role of integrin α(IIb)β(3) signaling to Syk kinase in tissue factor-induced thrombin generation

Por van der Meijden, Paola E. J., Feijge, Marion A. H., Swieringa, Frauke, Gilio, Karen, Nergiz-Unal, Reyhan, Hamulyák, Karly, Heemskerk, Johan W. M.
Publicado em 2012

Plasminogen associates with phosphatidylserine-exposing platelets and contributes to thrombus lysis under flow

Por Whyte, Claire S., Swieringa, Frauke, Mastenbroek, Tom G., Lionikiene, Ausra S., Lancé, Marcus D., van der Meijden, Paola E. J., Heemskerk, Johan W. M., Mutch, Nicola J.
Publicado no Blood (2015)

Combined Quantification of the Global Proteome, Phosphoproteome, and Proteolytic Cleavage to Characterize Altered Platelet Functions in the Human Scott Syndrome

Por Solari, Fiorella A., Mattheij, Nadine J.A., Burkhart, Julia M., Swieringa, Frauke, Collins, Peter W., Cosemans, Judith M.E.M., Sickmann, Albert, Heemskerk, Johan W.M., Zahedi, René P.
Publicado no Mol Cell Proteomics (2016)

Suppressive Role of Tissue Factor Pathway Inhibitor-α in Platelet-Dependent Fibrin Formation under Flow Is Restricted to Low Procoagulant Strength

Por Thomassen, Stella, Mastenbroek, Tom G., Swieringa, Frauke, Winckers, Kristien, Feijge, Marion A.H., Schrijver, Roy, Cosemans, Judith M.E.M., Maroney, Susan A., Mast, Alan E., Hackeng, Tilman M., Heemskerk, Johan W.M.
Publicado no Thromb Haemost (2018)

Platelet heterogeneity in activation-induced glycoprotein shedding: functional effects

Por Baaten, Constance C. F. M. J., Swieringa, Frauke, Misztal, Tomasz, Mastenbroek, Tom G., Feijge, Marion A. H., Bock, Paul E., Donners, Marjo M. P. C., Collins, Peter W., Li, Renhao, van der Meijden, Paola E. J., Heemskerk, Johan W. M.
Publicado no Blood Adv (2018)

Gradual increase in thrombogenicity of juvenile platelets formed upon offset of prasugrel medication

Por Baaten, Constance C. F. M. J., Veenstra, Leo F., Wetzels, Rick, van Geffen, Johanna P., Swieringa, Frauke, de Witt, Susanne M., Henskens, Yvonne M. C., Crijns, Harry, Nylander, Sven, van Giezen, J. J. J., Heemskerk, Johan W. M., van der Meijden, Paola E. J.
Publicado no Haematologica (2015)

AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation

Por Lepropre, Sophie, Kautbally, Shakeel, Octave, Marie, Ginion, Audrey, Onselaer, Marie-Blanche, Steinberg, Gregory R., Kemp, Bruce E., Hego, Alexandre, Wéra, Odile, Brouns, Sanne, Swieringa, Frauke, Giera, Martin, Darley-Usmar, Victor M., Ambroise, Jérôme, Guigas, Bruno, Heemskerk, Johan, Bertrand, Luc, Oury, Cécile, Beauloye, Christophe, Horman, Sandrine
Publicado no Blood (2018)

Identification of platelet function defects by multi-parameter assessment of thrombus formation

Por de Witt, Susanne M., Swieringa, Frauke, Cavill, Rachel, Lamers, Moniek M. E., van Kruchten, Roger, Mastenbroek, Tom, Baaten, Constance, Coort, Susan, Pugh, Nicholas, Schulz, Ansgar, Scharrer, Inge, Jurk, Kerstin, Zieger, Barbara, Clemetson, Kenneth J., Farndale, Richard W., Heemskerk, Johan W. M., Cosemans, Judith M.E.M.
Publicado em 2014

Impaired mitochondrial activity explains platelet dysfunction in thrombocytopenic cancer patients undergoing chemotherapy

Por Baaten, Constance C. F. M. J., Moenen, Floor C. J. I., Henskens, Yvonne M. C., Swieringa, Frauke, Wetzels, Rick J. H., van Oerle, René, Heijnen, Harry F. G., ten Cate, Hugo, Holloway, Graham P., Beckers, Erik A. M., Heemskerk, Johan W. M., van der Meijden, Paola E. J.
Publicado no Haematologica (2018)

Mild hyperlipidemia in mice aggravates platelet responsiveness in thrombus formation and exploration of platelet proteome and lipidome

Por van Geffen, Johanna P., Swieringa, Frauke, van Kuijk, Kim, Tullemans, Bibian M. E., Solari, Fiorella A., Peng, Bing, Clemetson, Kenneth J., Farndale, Richard W., Dubois, Ludwig J., Sickmann, Albert, Zahedi, René P., Ahrends, Robert, Biessen, Erik A. L., Sluimer, Judith C., Heemskerk, Johan W. M., Kuijpers, Marijke J. E.
Publicado no Sci Rep (2020)

Platelet-primed interactions of coagulation and anticoagulation pathways in flow-dependent thrombus formation

Por Brouns, Sanne L. N., van Geffen, Johanna P., Campello, Elena, Swieringa, Frauke, Spiezia, Luca, van Oerle, René, Provenzale, Isabella, Verdoold, Remco, Farndale, Richard W., Clemetson, Kenneth J., Spronk, Henri M. H., van der Meijden, Paola E. J., Cavill, Rachel, Kuijpers, Marijke J. E., Castoldi, Elisabetta, Simioni, Paolo, Heemskerk, Johan W. M.
Publicado no Sci Rep (2020)

High-throughput elucidation of thrombus formation reveals sources of platelet function variability

Por van Geffen, Johanna P., Brouns, Sanne L.N., Batista, Joana, McKinney, Harriet, Kempster, Carly, Nagy, Magdolna, Sivapalaratnam, Suthesh, Baaten, Constance C.F.M.J., Bourry, Nikki, Frontini, Mattia, Jurk, Kerstin, Krause, Manuela, Pillitteri, Daniele, Swieringa, Frauke, Verdoold, Remco, Cavill, Rachel, Kuijpers, Marijke J. E., Ouwehand, Willem H., Downes, Kate, Heemskerk, Johan W.M.
Publicado no Haematologica (2019)

Coated platelets function in platelet-dependent fibrin formation via integrin α(IIb)β(3) and transglutaminase factor XIII

Por Mattheij, Nadine J.A., Swieringa, Frauke, Mastenbroek, Tom G., Berny-Lang, Michelle A., May, Frauke, Baaten, Constance C.F.M.J., van der Meijden, Paola E.J., Henskens, Yvonne M.C., Beckers, Erik A.M., Suylen, Dennis P.L., Nolte, Marc W., Hackeng, Tilman M., McCarty, Owen J.T., Heemskerk, Johan W.M., Cosemans, Judith M.E.M.
Publicado no Haematologica (2016)

Impaired iloprost-induced platelet inhibition and phosphoproteome changes in patients with confirmed pseudohypoparathyroidism type Ia, linked to genetic mutations in GNAS

Por Swieringa, Frauke, Solari, Fiorella A., Pagel, Oliver, Beck, Florian, Huang, Jingnan, Feijge, Marion A. H., Jurk, Kerstin, Körver-Keularts, Irene M. L. W., Mattheij, Nadine J. A., Faber, Jörg, Pohlenz, Joachim, Russo, Alexandra, Stumpel, Connie T. R. M., Schrander, Dirk E., Zieger, Barbara, van der Meijden, Paola E. J., Zahedi, René P., Sickmann, Albert, Heemskerk, Johan W. M.
Publicado no Sci Rep (2020)

A synthesis approach of mouse studies to identify genes and proteins in arterial thrombosis and bleeding

Por Baaten, Constance C. F. M. J., Meacham, Stuart, de Witt, Susanne M., Feijge, Marion A. H., Adams, David J., Akkerman, Jan-Willem N., Cosemans, Judith M. E. M., Grassi, Luigi, Jupe, Steve, Kostadima, Myrto, Mattheij, Nadine J. A., Prins, Martin H., Ramirez-Solis, Ramiro, Soehnlein, Oliver, Swieringa, Frauke, Weber, Christian, White, Jacqueline K., Ouwehand, Willem H., Heemskerk, Johan W. M.
Publicado no Blood (2018)