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Impaired mitochondrial activity explains platelet dysfunction in thrombocytopenic cancer patients undergoing chemotherapy

Severe thrombocytopenia (≤50×10(9) platelets/L) due to hematological malignancy and intensive chemotherapy is associated with an increased risk of clinically significant bleeding. Since the bleeding risk is not linked to the platelet count only, other hemostatic factors must be involved. We studied...

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Τόπος έκδοσης:	Haematologica
Κύριοι συγγραφείς:	Baaten, Constance C. F. M. J., Moenen, Floor C. J. I., Henskens, Yvonne M. C., Swieringa, Frauke, Wetzels, Rick J. H., van Oerle, René, Heijnen, Harry F. G., ten Cate, Hugo, Holloway, Graham P., Beckers, Erik A. M., Heemskerk, Johan W. M., van der Meijden, Paola E. J.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Ferrata Storti Foundation 2018
Θέματα:	Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6119160/ https://ncbi.nlm.nih.gov/pubmed/29880611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2017.185165
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Impaired mitochondrial activity explains platelet dysfunction in thrombocytopenic cancer patients undergoing chemotherapy

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