Impaired mitochondrial activity explains platelet dysfunction in thrombocytopenic cancer patients undergoing chemotherapy

Severe thrombocytopenia (≤50×10(9) platelets/L) due to hematological malignancy and intensive chemotherapy is associated with an increased risk of clinically significant bleeding. Since the bleeding risk is not linked to the platelet count only, other hemostatic factors must be involved. We studied...

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Publicado no:Haematologica
Main Authors: Baaten, Constance C. F. M. J., Moenen, Floor C. J. I., Henskens, Yvonne M. C., Swieringa, Frauke, Wetzels, Rick J. H., van Oerle, René, Heijnen, Harry F. G., ten Cate, Hugo, Holloway, Graham P., Beckers, Erik A. M., Heemskerk, Johan W. M., van der Meijden, Paola E. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6119160/
https://ncbi.nlm.nih.gov/pubmed/29880611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2017.185165
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