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Variable impairment of platelet functions in patients with severe, genetically linked immune deficiencies

In patients with dysfunctions of the Ca(2+) channel ORAI1, stromal interaction molecule 1 (STIM1) or integrin-regulating kindlin-3 (FERMT3), severe immunodeficiency is frequently linked to abnormal platelet activity. In this paper, we studied platelet responsiveness by multiparameter assessment of w...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Nagy, Magdolna, Mastenbroek, Tom G., Mattheij, Nadine J.A., de Witt, Susanne, Clemetson, Kenneth J., Kirschner, Janbernd, Schulz, Ansgar S., Vraetz, Thomas, Speckmann, Carsten, Braun, Attila, Cosemans, Judith M.E.M., Zieger, Barbara, Heemskerk, Johan W.M.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830379/
https://ncbi.nlm.nih.gov/pubmed/29242293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2017.176974
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