Mitochondrially Mediated Integrin α(IIb)β(3) Protein Inactivation Limits Thrombus Growth

When platelets are strongly stimulated, a procoagulant platelet subpopulation is formed that is characterized by phosphatidylserine (PS) exposure and epitope modulation of integrin α(IIb)β(3) or a loss of binding of activation-dependent antibodies. Mitochondrial permeability transition pore (mPTP) f...

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Autores principales: Liu, Fang, Gamez, Graciela, Myers, David R., Clemmons, Wayne, Lam, Wilbur A., Jobe, Shawn M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798537/
https://ncbi.nlm.nih.gov/pubmed/24014035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.472688
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