Protein Phosphatase 2A Negatively Regulates Integrin α(IIb)β(3) Signaling

Integrin α(IIb)β(3) activation is critical for platelet physiology and is controlled by signal transduction through kinases and phosphatases. Compared with kinases, a role for phosphatases in platelet integrin α(IIb)β(3) signaling is less understood. We report that the catalytic subunit of protein p...

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Detalhes bibliográficos
Main Authors: Gushiken, Francisca C., Patel, Vimal, Liu, Yan, Pradhan, Subhashree, Bergeron, Angela L., Peng, Yuandong, Vijayan, K. Vinod
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442329/
https://ncbi.nlm.nih.gov/pubmed/18334487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708804200
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