Cross-talk between Serine/Threonine Protein Phosphatase 2A and Protein Tyrosine Phosphatase 1B Regulates Src Activation and Adhesion of Integrin α(IIb)β(3) to Fibrinogen

Integrin α(IIb)β(3) signaling mediated by kinases and phosphatases participate in hemostasis and thrombosis, in part, by supporting stable platelet adhesion. Our previous studies indicate that the genetic manipulation of PP2Acα (α isoform of the catalytic subunit of protein phosphatase 2A) negativel...

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Detalhes bibliográficos
Main Authors: Pradhan, Subhashree, Alrehani, Nawaf, Patel, Vimal, Khatlani, Tanvir, Vijayan, K. Vinod
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937937/
https://ncbi.nlm.nih.gov/pubmed/20615878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.085167
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