Wird geladen...

Distinct Roles for the α, β and γ1 isoforms of Protein Phosphatase 1 in the Outside-in α(IIb)β(3) Integrin Signaling Dependent Functions

Although protein kinases and phosphatases participate in integrin α(IIb)β(3) signaling, whether integrin functions are regulated by the catalytic subunit of protein phosphatase 1 (PP1c) isoforms are unclear. We show that siRNA mediated knockdown of all PP1c isoforms (α, β and γ1) in 293 α(IIb)β(3) c...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Alrehani, Nawaf, Pradhan, Subhashree, Khatlani, Tanvir, Kailasam, Lavanya, Vijayan, K. Vinod
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749075/
https://ncbi.nlm.nih.gov/pubmed/23197154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH12-04-0237
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!