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Distinct Roles for the α, β and γ1 isoforms of Protein Phosphatase 1 in the Outside-in α(IIb)β(3) Integrin Signaling Dependent Functions
Although protein kinases and phosphatases participate in integrin α(IIb)β(3) signaling, whether integrin functions are regulated by the catalytic subunit of protein phosphatase 1 (PP1c) isoforms are unclear. We show that siRNA mediated knockdown of all PP1c isoforms (α, β and γ1) in 293 α(IIb)β(3) c...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3749075/ https://ncbi.nlm.nih.gov/pubmed/23197154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH12-04-0237 |
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