Dok-2 Adaptor Protein Regulates the Shear-dependent Adhesive Function of Platelet Integrin α(IIb)β(3) in Mice

The Dok proteins are a family of adaptor molecules that have a well defined role in regulating cellular migration, immune responses, and tumor progression. Previous studies have demonstrated that Doks-1 to 3 are expressed in platelets and that Dok-2 is tyrosine-phosphorylated downstream of integrin...

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Bibliografiska uppgifter
Huvudupphovsmän: Hughan, Sascha C., Spring, Christopher M., Schoenwaelder, Simone M., Sturgeon, Sharelle, Alwis, Imala, Yuan, Yuping, McFadyen, James D., Westein, Erik, Goddard, Duncan, Ono, Akiko, Yamanashi, Yuji, Nesbitt, Warwick S., Jackson, Shaun P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2014
Ämnen:
Signal Transduction
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931064/
https://ncbi.nlm.nih.gov/pubmed/24385425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.520148
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