Dok-2 Adaptor Protein Regulates the Shear-dependent Adhesive Function of Platelet Integrin α(IIb)β(3) in Mice

The Dok proteins are a family of adaptor molecules that have a well defined role in regulating cellular migration, immune responses, and tumor progression. Previous studies have demonstrated that Doks-1 to 3 are expressed in platelets and that Dok-2 is tyrosine-phosphorylated downstream of integrin...

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Detalhes bibliográficos
Main Authors: Hughan, Sascha C., Spring, Christopher M., Schoenwaelder, Simone M., Sturgeon, Sharelle, Alwis, Imala, Yuan, Yuping, McFadyen, James D., Westein, Erik, Goddard, Duncan, Ono, Akiko, Yamanashi, Yuji, Nesbitt, Warwick S., Jackson, Shaun P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931064/
https://ncbi.nlm.nih.gov/pubmed/24385425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.520148
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