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Phosphoinositide 3-Kinase p110β Regulates Integrin α(IIb)β(3) Avidity and the Cellular Transmission of Contractile Forces
Phosphoinositide (PI) 3-kinase (PI3K) signaling processes play an important role in regulating the adhesive function of integrin α(IIb)β(3), necessary for platelet spreading and sustained platelet aggregation. PI3K inhibitors are effective at reducing platelet aggregation and thrombus formation in v...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2807342/ https://ncbi.nlm.nih.gov/pubmed/19940148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.029132 |
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