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Integrin α(IIb)β(3) outside-in signaling

Integrin α(IIb)β(3) is a highly abundant heterodimeric platelet receptor that can transmit information bidirectionally across the plasma membrane, and plays a critical role in hemostasis and thrombosis. Upon platelet activation, inside-out signaling pathways increase the affinity of α(IIb)β(3) for f...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Blood
Prif Awduron: Durrant, Tom N., van den Bosch, Marion T., Hers, Ingeborg
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672329/
https://ncbi.nlm.nih.gov/pubmed/28794070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-03-773614
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