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Key role of integrin α(IIb)β(3) signaling to Syk kinase in tissue factor-induced thrombin generation
The fibrin(ogen) receptor, integrin α(IIb)β(3), has a well-established role in platelet spreading, aggregation and clot retraction. How α(IIb)β(3) contributes to platelet-dependent coagulation is less well resolved. Here, we demonstrate that the potent suppressing effect of clinically used α(IIb)β(3...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
SP Birkhäuser Verlag Basel
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3445795/ https://ncbi.nlm.nih.gov/pubmed/22669259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-012-1033-2 |
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