Integrating platelet and coagulation activation in fibrin clot formation

Autor Swieringa, Frauke, Spronk, Henri M.H., Heemskerk, Johan W.M., van der Meijden, Paola E.J.
Vydáno v Res Pract Thromb Haemost (2018)

Whole Blood Based Multiparameter Assessment of Thrombus Formation in Standard Microfluidic Devices to Proxy In Vivo Haemostasis and Thrombosis

Autor Provenzale, Isabella, Brouns, Sanne L. N., van der Meijden, Paola E. J., Swieringa, Frauke, Heemskerk, Johan W. M.
Vydáno v Micromachines (Basel) (2019)

Rate-limiting roles of the tenase complex of factors VIII and IX in platelet procoagulant activity and formation of platelet-fibrin thrombi under flow

Autor Swieringa, Frauke, Kuijpers, Marijke J. E., Lamers, Moniek M. E., van der Meijden, Paola E. J., Heemskerk, Johan W. M.
Vydáno v Haematologica (2015)

Key role of integrin α(IIb)β(3) signaling to Syk kinase in tissue factor-induced thrombin generation

Autor van der Meijden, Paola E. J., Feijge, Marion A. H., Swieringa, Frauke, Gilio, Karen, Nergiz-Unal, Reyhan, Hamulyák, Karly, Heemskerk, Johan W. M.
Vydáno 2012

Plasminogen associates with phosphatidylserine-exposing platelets and contributes to thrombus lysis under flow

Autor Whyte, Claire S., Swieringa, Frauke, Mastenbroek, Tom G., Lionikiene, Ausra S., Lancé, Marcus D., van der Meijden, Paola E. J., Heemskerk, Johan W. M., Mutch, Nicola J.
Vydáno v Blood (2015)

Combined Quantification of the Global Proteome, Phosphoproteome, and Proteolytic Cleavage to Characterize Altered Platelet Functions in the Human Scott Syndrome

Autor Solari, Fiorella A., Mattheij, Nadine J.A., Burkhart, Julia M., Swieringa, Frauke, Collins, Peter W., Cosemans, Judith M.E.M., Sickmann, Albert, Heemskerk, Johan W.M., Zahedi, René P.
Vydáno v Mol Cell Proteomics (2016)

Assessment of a complete and classified platelet proteome from genome-wide transcripts of human platelets and megakaryocytes covering platelet functions

Autor Huang, Jingnan, Swieringa, Frauke, Solari, Fiorella A., Provenzale, Isabella, Grassi, Luigi, De Simone, Ilaria, Baaten, Constance C. F. M. J., Cavill, Rachel, Sickmann, Albert, Frontini, Mattia, Heemskerk, Johan W. M.
Vydáno v Sci Rep (2021)

Suppressive Role of Tissue Factor Pathway Inhibitor-α in Platelet-Dependent Fibrin Formation under Flow Is Restricted to Low Procoagulant Strength

Autor Thomassen, Stella, Mastenbroek, Tom G., Swieringa, Frauke, Winckers, Kristien, Feijge, Marion A.H., Schrijver, Roy, Cosemans, Judith M.E.M., Maroney, Susan A., Mast, Alan E., Hackeng, Tilman M., Heemskerk, Johan W.M.
Vydáno v Thromb Haemost (2018)

Platelet heterogeneity in activation-induced glycoprotein shedding: functional effects

Autor Baaten, Constance C. F. M. J., Swieringa, Frauke, Misztal, Tomasz, Mastenbroek, Tom G., Feijge, Marion A. H., Bock, Paul E., Donners, Marjo M. P. C., Collins, Peter W., Li, Renhao, van der Meijden, Paola E. J., Heemskerk, Johan W. M.
Vydáno v Blood Adv (2018)

Gradual increase in thrombogenicity of juvenile platelets formed upon offset of prasugrel medication

Autor Baaten, Constance C. F. M. J., Veenstra, Leo F., Wetzels, Rick, van Geffen, Johanna P., Swieringa, Frauke, de Witt, Susanne M., Henskens, Yvonne M. C., Crijns, Harry, Nylander, Sven, van Giezen, J. J. J., Heemskerk, Johan W. M., van der Meijden, Paola E. J.
Vydáno v Haematologica (2015)

AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation

Autor Lepropre, Sophie, Kautbally, Shakeel, Octave, Marie, Ginion, Audrey, Onselaer, Marie-Blanche, Steinberg, Gregory R., Kemp, Bruce E., Hego, Alexandre, Wéra, Odile, Brouns, Sanne, Swieringa, Frauke, Giera, Martin, Darley-Usmar, Victor M., Ambroise, Jérôme, Guigas, Bruno, Heemskerk, Johan, Bertrand, Luc, Oury, Cécile, Beauloye, Christophe, Horman, Sandrine
Vydáno v Blood (2018)

Identification of platelet function defects by multi-parameter assessment of thrombus formation

Autor de Witt, Susanne M., Swieringa, Frauke, Cavill, Rachel, Lamers, Moniek M. E., van Kruchten, Roger, Mastenbroek, Tom, Baaten, Constance, Coort, Susan, Pugh, Nicholas, Schulz, Ansgar, Scharrer, Inge, Jurk, Kerstin, Zieger, Barbara, Clemetson, Kenneth J., Farndale, Richard W., Heemskerk, Johan W. M., Cosemans, Judith M.E.M.
Vydáno 2014

Impaired mitochondrial activity explains platelet dysfunction in thrombocytopenic cancer patients undergoing chemotherapy

Autor Baaten, Constance C. F. M. J., Moenen, Floor C. J. I., Henskens, Yvonne M. C., Swieringa, Frauke, Wetzels, Rick J. H., van Oerle, René, Heijnen, Harry F. G., ten Cate, Hugo, Holloway, Graham P., Beckers, Erik A. M., Heemskerk, Johan W. M., van der Meijden, Paola E. J.
Vydáno v Haematologica (2018)

Mild hyperlipidemia in mice aggravates platelet responsiveness in thrombus formation and exploration of platelet proteome and lipidome

Autor van Geffen, Johanna P., Swieringa, Frauke, van Kuijk, Kim, Tullemans, Bibian M. E., Solari, Fiorella A., Peng, Bing, Clemetson, Kenneth J., Farndale, Richard W., Dubois, Ludwig J., Sickmann, Albert, Zahedi, René P., Ahrends, Robert, Biessen, Erik A. L., Sluimer, Judith C., Heemskerk, Johan W. M., Kuijpers, Marijke J. E.
Vydáno v Sci Rep (2020)

Platelet-primed interactions of coagulation and anticoagulation pathways in flow-dependent thrombus formation

Autor Brouns, Sanne L. N., van Geffen, Johanna P., Campello, Elena, Swieringa, Frauke, Spiezia, Luca, van Oerle, René, Provenzale, Isabella, Verdoold, Remco, Farndale, Richard W., Clemetson, Kenneth J., Spronk, Henri M. H., van der Meijden, Paola E. J., Cavill, Rachel, Kuijpers, Marijke J. E., Castoldi, Elisabetta, Simioni, Paolo, Heemskerk, Johan W. M.
Vydáno v Sci Rep (2020)

High-throughput elucidation of thrombus formation reveals sources of platelet function variability

Autor van Geffen, Johanna P., Brouns, Sanne L.N., Batista, Joana, McKinney, Harriet, Kempster, Carly, Nagy, Magdolna, Sivapalaratnam, Suthesh, Baaten, Constance C.F.M.J., Bourry, Nikki, Frontini, Mattia, Jurk, Kerstin, Krause, Manuela, Pillitteri, Daniele, Swieringa, Frauke, Verdoold, Remco, Cavill, Rachel, Kuijpers, Marijke J. E., Ouwehand, Willem H., Downes, Kate, Heemskerk, Johan W.M.
Vydáno v Haematologica (2019)

Coated platelets function in platelet-dependent fibrin formation via integrin α(IIb)β(3) and transglutaminase factor XIII

Autor Mattheij, Nadine J.A., Swieringa, Frauke, Mastenbroek, Tom G., Berny-Lang, Michelle A., May, Frauke, Baaten, Constance C.F.M.J., van der Meijden, Paola E.J., Henskens, Yvonne M.C., Beckers, Erik A.M., Suylen, Dennis P.L., Nolte, Marc W., Hackeng, Tilman M., McCarty, Owen J.T., Heemskerk, Johan W.M., Cosemans, Judith M.E.M.
Vydáno v Haematologica (2016)

Impaired iloprost-induced platelet inhibition and phosphoproteome changes in patients with confirmed pseudohypoparathyroidism type Ia, linked to genetic mutations in GNAS

Autor Swieringa, Frauke, Solari, Fiorella A., Pagel, Oliver, Beck, Florian, Huang, Jingnan, Feijge, Marion A. H., Jurk, Kerstin, Körver-Keularts, Irene M. L. W., Mattheij, Nadine J. A., Faber, Jörg, Pohlenz, Joachim, Russo, Alexandra, Stumpel, Connie T. R. M., Schrander, Dirk E., Zieger, Barbara, van der Meijden, Paola E. J., Zahedi, René P., Sickmann, Albert, Heemskerk, Johan W. M.
Vydáno v Sci Rep (2020)

A synthesis approach of mouse studies to identify genes and proteins in arterial thrombosis and bleeding

Autor Baaten, Constance C. F. M. J., Meacham, Stuart, de Witt, Susanne M., Feijge, Marion A. H., Adams, David J., Akkerman, Jan-Willem N., Cosemans, Judith M. E. M., Grassi, Luigi, Jupe, Steve, Kostadima, Myrto, Mattheij, Nadine J. A., Prins, Martin H., Ramirez-Solis, Ramiro, Soehnlein, Oliver, Swieringa, Frauke, Weber, Christian, White, Jacqueline K., Ouwehand, Willem H., Heemskerk, Johan W. M.
Vydáno v Blood (2018)