Structural basis of Ac-SDKP hydrolysis by Angiotensin-I converting enzyme

Por Masuyer, Geoffrey, Douglas, Ross G., Sturrock, Edward D., Acharya, K. Ravi
Publicado no Sci Rep (2015)

Molecular recognition and regulation of human angiotensin-I converting enzyme (ACE) activity by natural inhibitory peptides

Por Masuyer, Geoffrey, Schwager, Sylva L. U., Sturrock, Edward D., Isaac, R. Elwyn, Acharya, K. Ravi
Publicado em 2012

Structural basis of peptide recognition by the angiotensin-1 converting enzyme homologue AnCE from Drosophila melanogaster

Por Akif, Mohd, Masuyer, Geoffrey, Bingham, Richard J, Sturrock, Edward D, Isaac, R Elwyn, Acharya, K Ravi
Publicado em 2012

Molecular and Thermodynamic Mechanisms of the Chloride-dependent Human Angiotensin-I-converting Enzyme (ACE)

Por Yates, Christopher J., Masuyer, Geoffrey, Schwager, Sylva L. U., Akif, Mohd, Sturrock, Edward D., Acharya, K. Ravi
Publicado em 2014

Kinetic and structural characterization of amyloid‐β peptide hydrolysis by human angiotensin‐1‐converting enzyme

Por Larmuth, Kate M., Masuyer, Geoffrey, Douglas, Ross G., Schwager, Sylva L., Acharya, K. Ravi, Sturrock, Edward D.
Publicado no FEBS J (2016)

The N domain of somatic angiotensin-converting enzyme negatively regulates ectodomain shedding and catalytic activity

Por Woodman, Zenda L., Schwager, Sylva L. U., Redelinghuys, Pierre, Carmona, Adriana K., Ehlers, Mario R. W., Sturrock, Edward D.
Publicado em 2005

Novel mechanism of inhibition of human angiotensin-I-converting enzyme (ACE) by a highly specific phosphinic tripeptide

Por Akif, Mohd, Schwager, Sylva L., Anthony, Colin S., Czarny, Bertrand, Beau, Fabrice, Dive, Vincent, Sturrock, Edward D., Acharya, K. Ravi
Publicado em 2011

Crystal Structure of Protoporphyrinogen Oxidase from Myxococcus Xanthus and its Complex with the Inhibitor Acifluorfen

Por Corradi, Hazel R., Corrigall, Anne V., Boix, Ester, Mohan, C. Gopi, Sturrock, Edward D., Meissner, Peter N., Acharya, K. Ravi
Publicado em 2006

Structure of testis ACE glycosylation mutants and evidence for conserved domain movement

Por Watermeyer, Jean M., Sewell, B. Trevor, Schwager, Sylva L., Natesh, Ramanathan, Corradi, Hazel R., Acharya, K. Ravi, Sturrock, Edward D.
Publicado em 2006

Fragment-based design for the development of N-domain-selective angiotensin-1-converting enzyme inhibitors

Por Douglas, Ross G., Sharma, Rajni K., Masuyer, Geoffrey, Lubbe, Lizelle, Zamora, Ismael, Acharya, K. Ravi, Chibale, Kelly, Sturrock, Edward D.
Publicado em 2013

Interkingdom Pharmacology of Angiotensin-I Converting Enzyme Inhibitor Phosphonates Produced by Actinomycetes

Por Kramer, Glenna J., Mohd, Akif, Schwager, Sylva L. U., Masuyer, Geoffrey, Acharya, K. Ravi, Sturrock, Edward D., Bachmann, Brian O.
Publicado em 2014

A Pilot Study of Ac-SDKP (N-acetyl-seryl-aspartyl-lysyl-proline) and Galectin-3 Levels in Normal Pericardial Fluid and Tuberculous Pericardial Effusion: Implications for Pathogenes...

Por Ntsekhe, Mpiko, Matthews, Kerryn, Wolske, Janine, Badri, Motasim, Wilkinson, Katalin A, Wilkinson, Robert J, Sturrock, Edward D, Mayosi, Bongani M
Publicado em 2012

The N Domain of Human Angiotensin-I-converting Enzyme: THE ROLE OF N-GLYCOSYLATION AND THE CRYSTAL STRUCTURE IN COMPLEX WITH AN N DOMAIN-SPECIFIC PHOSPHINIC INHIBITOR, RXP407

Por Anthony, Colin S., Corradi, Hazel R., Schwager, Sylva L. U., Redelinghuys, Pierre, Georgiadis, Dimitris, Dive, Vincent, Acharya, K. Ravi, Sturrock, Edward D.
Publicado em 2010

Structural characterization of angiotensin I-converting enzyme in complex with a selenium analogue of captopril

Por Akif, Mohd, Masuyer, Geoffrey, Schwager, Sylva L U, Bhuyan, Bhaskar J, Mugesh, Govindasamy, Isaac, R Elwyn, Sturrock, Edward D, Acharya, K Ravi
Publicado em 2011

Deglycosylation, processing and crystallization of human testis angiotensin-converting enzyme.

Por Gordon, Kerry, Redelinghuys, Pierre, Schwager, Sylva L U, Ehlers, Mario R W, Papageorgiou, Anastassios C, Natesh, Ramanathan, Acharya, K Ravi, Sturrock, Edward D
Publicado em 2003

Crystal structures of highly specific phosphinic tripeptide enantiomers in complex with the angiotensin‐I converting enzyme

Por Masuyer, Geoffrey, Akif, Mohd, Czarny, Bertrand, Beau, Fabrice, Schwager, Sylva L. U., Sturrock, Edward D., Isaac, R. Elwyn, Dive, Vincent, Acharya, K. Ravi
Publicado em 2013

A Novel Angiotensin I-Converting Enzyme Mutation (S333W) Impairs N-Domain Enzymatic Cleavage of the Anti-Fibrotic Peptide, AcSDKP

Por Danilov, Sergei M., Wade, Michael S., Schwager, Sylva L., Douglas, Ross G., Nesterovitch, Andrew B., Popova, Isolda A., Hogarth, Kyle D., Bhardwaj, Nakul, Schwartz, David E., Sturrock, Edward D., Garcia, Joe G. N.
Publicado em 2014

An Angiotensin I-Converting Enzyme Mutation (Y465D) Causes a Dramatic Increase in Blood ACE via Accelerated ACE Shedding

Por Danilov, Sergei M., Gordon, Kerry, Nesterovitch, Andrew B., Lünsdorf, Heinrich, Chen, Zhenlong, Castellon, Maricela, Popova, Isolda A., Kalinin, Sergey, Mendonca, Emma, Petukhov, Pavel A., Schwartz, David E., Minshall, Richard D., Sturrock, Edward D.
Publicado em 2011