Novel mechanism of inhibition of human angiotensin-I-converting enzyme (ACE) by a highly specific phosphinic tripeptide

Human ACE (angiotensin-I-converting enzyme) has long been regarded as an excellent target for the treatment of hypertension and related cardiovascular diseases. Highly potent inhibitors have been developed and are extensively used in the clinic. To develop inhibitors with higher therapeutic efficacy...

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Bibliografski detalji
Glavni autori: Akif, Mohd, Schwager, Sylva L., Anthony, Colin S., Czarny, Bertrand, Beau, Fabrice, Dive, Vincent, Sturrock, Edward D., Acharya, K. Ravi
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2011
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086271/
https://ncbi.nlm.nih.gov/pubmed/21352096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20102123
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