Crystal structures of highly specific phosphinic tripeptide enantiomers in complex with the angiotensin‐I converting enzyme

Human somatic angiotensin‐I converting enzyme (ACE) is a zinc‐dependent dipeptidyl carboxypeptidase and a central component of the renin angiotensin aldosterone system (RAAS). Its involvement in the modulation of physiological actions of peptide hormones has positioned ACE as an important therapeuti...

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Detalhes bibliográficos
Main Authors: Masuyer, Geoffrey, Akif, Mohd, Czarny, Bertrand, Beau, Fabrice, Schwager, Sylva L. U., Sturrock, Edward D., Isaac, R. Elwyn, Dive, Vincent, Acharya, K. Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies 2013
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154125/
https://ncbi.nlm.nih.gov/pubmed/24289879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12660
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