Molecular and Thermodynamic Mechanisms of the Chloride-dependent Human Angiotensin-I-converting Enzyme (ACE)

Somatic angiotensin-converting enzyme (sACE), a key regulator of blood pressure and electrolyte fluid homeostasis, cleaves the vasoactive angiotensin-I, bradykinin, and a number of other physiologically relevant peptides. sACE consists of two homologous and catalytically active N- and C-domains, whi...

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Hlavní autoři: Yates, Christopher J., Masuyer, Geoffrey, Schwager, Sylva L. U., Akif, Mohd, Sturrock, Edward D., Acharya, K. Ravi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Enzymology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894356/
https://ncbi.nlm.nih.gov/pubmed/24297181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.512335
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