An Angiotensin I-Converting Enzyme Mutation (Y465D) Causes a Dramatic Increase in Blood ACE via Accelerated ACE Shedding

BACKGROUND: Angiotensin I-converting enzyme (ACE) metabolizes a range of peptidic substrates and plays a key role in blood pressure regulation and vascular remodeling. Thus, elevated ACE levels may be associated with an increased risk for different cardiovascular or respiratory diseases. Previously,...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Danilov, Sergei M., Gordon, Kerry, Nesterovitch, Andrew B., Lünsdorf, Heinrich, Chen, Zhenlong, Castellon, Maricela, Popova, Isolda A., Kalinin, Sergey, Mendonca, Emma, Petukhov, Pavel A., Schwartz, David E., Minshall, Richard D., Sturrock, Edward D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2011
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187827/
https://ncbi.nlm.nih.gov/pubmed/21998728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025952
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