Lysozyme and bilirubin bind to ACE and regulate its conformation and shedding

Angiotensin I-converting enzyme (ACE) hydrolyzes numerous peptides and is a critical participant in blood pressure regulation and vascular remodeling. Elevated tissue ACE levels are associated with increased risk for cardiovascular and respiratory disorders. Blood ACE concentrations are determined b...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Danilov, Sergei M., Lünsdorf, Heinrich, Akinbi, Henry T., Nesterovitch, Andrew B., Epshtein, Yuliya, Letsiou, Eleftheria, Kryukova, Olga V., Piegeler, Tobias, Golukhova, Elena Z., Schwartz, David E., Dull, Randal O., Minshall, Richard D., Kost, Olga A., Garcia, Joe G. N.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062130/
https://ncbi.nlm.nih.gov/pubmed/27734897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34913
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