Cathepsin D Primes Caspase-8 Activation by Multiple Intra-chain Proteolysis

Por Conus, Sébastien, Pop, Cristina, Snipas, Scott J., Salvesen, Guy S., Simon, Hans-Uwe
Publicado em 2012

Unnatural amino acids increase sensitivity and provide for the design of highly selective caspase substrates

Por Poreba, M, Kasperkiewicz, P, Snipas, S J, Fasci, D, Salvesen, G S, Drag, M
Publicado em 2014

Caspase selective reagents for diagnosing apoptotic mechanisms

Por Poreba, Marcin, Groborz, Katarzyna, Navarro, Mario, Snipas, Scott J., Drag, Marcin, Salvesen, Guy S.
Publicado no Cell Death Differ (2018)

Inhibition of distant caspase homologues by natural caspase inhibitors.

Por Snipas, S J, Stennicke, H R, Riedl, S, Potempa, J, Travis, J, Barrett, A J, Salvesen, G S
Publicado em 2001

Design of a Selective Substrate and Activity Based Probe for Human Neutrophil Serine Protease 4

Por Kasperkiewicz, Paulina, Poreba, Marcin, Snipas, Scott J., Lin, S. Jack, Kirchhofer, Daniel, Salvesen, Guy S., Drag, Marcin
Publicado no PLoS One (2015)

Extensive peptide and natural protein substrate screens reveal that mouse caspase-11 has much narrower substrate specificity than caspase-1

Por Ramirez, Monica L. Gonzalez, Poreba, Marcin, Snipas, Scott J., Groborz, Katarzyna, Drag, Marcin, Salvesen, Guy S.
Publicado no J Biol Chem (2018)

Activation-coupled membrane-type 1 matrix metalloproteinase membrane trafficking

Por Wu, Yi I., Munshi, Hidayatullah G., Snipas, Scott J., Salvesen, Guy S., Fridman, Rafael, Stack, M. Sharon
Publicado em 2007

Design of ultrasensitive probes for human neutrophil elastase through hybrid combinatorial substrate library profiling

Por Kasperkiewicz, Paulina, Poreba, Marcin, Snipas, Scott J., Parker, Heather, Winterbourn, Christine C., Salvesen, Guy S., Drag, Marcin
Publicado em 2014

Determination of extended substrate specificity of the MALT1 as a strategy for the design of potent substrates and activity-based probes

Por Kasperkiewicz, Paulina, Kołt, Sonia, Janiszewski, Tomasz, Groborz, Katarzyna, Poręba, Marcin, Snipas, Scott J., Salvesen, Guy S., Drąg, Marcin
Publicado no Sci Rep (2018)

Structural and kinetic determinants of protease substrates

Por Timmer, John C., Zhu, Wenhong, Pop, Cristina, Regan, Tim, Snipas, Scott J., Eroshkin, Alexey M., Riedl, Stefan J., Salvesen, Guy S.
Publicado em 2009

Proteolytic activation of the cell death protease Yama/CPP32 by granzyme B.

Por Quan, L T, Tewari, M, O'Rourke, K, Dixit, V, Snipas, S J, Poirier, G G, Ray, C, Pickup, D J, Salvesen, G S
Publicado em 1996

Mechanism and specificity of the human paracaspase MALT1

Por Hachmann, Janna, Snipas, Scott J., van Raam, Bram J., Cancino, Erik M., Houlihan, Emily J., Poreba, Marcin, Kasperkiewicz, Paulina, Drag, Marcin, Salvesen, Guy S.
Publicado em 2012

Counter Selection Substrate Library Strategy for Developing Specific Protease Substrates and Probes

Por Poreba, Marcin, Solberg, Rigmor, Rut, Wioletta, Lunde, Ngoc Nguyen, Kasperkiewicz, Paulina, Snipas, Scott J., Mihelic, Marko, Turk, Dusan, Turk, Boris, Salvesen, Guy S., Drag, Marcin
Publicado no Cell Chem Biol (2016)

Activation and Specificity of human Caspase-10

Por Wachmann, Katherine, Pop, Cristina, van Raam, Bram J., Drag, Marcin, Mace, Peter D., Snipas, Scott J., Zmasek, Christian, Schwarzenbacher, Robert, Salvesen, Guy S., Riedl, Stefan J.
Publicado em 2010

Highly sensitive and adaptable fluorescence-quenched pair discloses the substrate specificity profiles in diverse protease families

Por Poreba, Marcin, Szalek, Aleksandra, Rut, Wioletta, Kasperkiewicz, Paulina, Rutkowska-Wlodarczyk, Izabela, Snipas, Scott J., Itoh, Yoshifumi, Turk, Dusan, Turk, Boris, Overall, Christopher M., Kaczmarek, Leszek, Salvesen, Guy S., Drag, Marcin
Publicado no Sci Rep (2017)

SHARPIN-mediated regulation of protein arginine methyltransferase 5 controls melanoma growth

Por Tamiya, Hironari, Kim, Hyungsoo, Klymenko, Oleksiy, Kim, Heejung, Feng, Yongmei, Zhang, Tongwu, Han, Jee Yun, Murao, Ayako, Snipas, Scott J., Jilaveanu, Lucia, Brown, Kevin, Kluger, Harriet, Zhang, Hao, Iwai, Kazuhiro, Ronai, Ze’ev A.
Publicado no J Clin Invest (2017)

Intranasal Delivery of Caspase-9 Inhibitor Reduces Caspase-6-Dependent Axon/Neuron Loss and Improves Neurological Function after Stroke

Por Akpan, Nsikan, Serrano-Saiz, Esther, Zacharia, Brad E., Otten, Marc L., Ducruet, Andrew F., Snipas, Scott J., Liu, Wen, Velloza, Jennifer, Cohen, Greg, Sosunov, Sergeyi A., Frey, William H., Salvesen, Guy S., Connolly, E. Sander, Troy, Carol M.
Publicado em 2011

Expedient Synthesis of Highly Potent Antagonists of Inhibitor of Apoptosis Proteins (IAPs) with Unique Selectivity for ML-IAP

Por Vamos, Mitchell, Welsh, Kate, Finlay, Darren, Lee, Pooi San, Mace, Peter D., Snipas, Scott J., Gonzalez, Monica L., Ganji, Santhi Reddy, Ardecky, Robert J., Riedl, Stefan J., Salvesen, Guy S., Vuori, Kristiina, Reed, John C., Cosford, Nicholas D. P.
Publicado em 2013