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Determination of extended substrate specificity of the MALT1 as a strategy for the design of potent substrates and activity-based probes

Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) belongs to the CD clan of cysteine proteases. MALT1 is a unique enzyme among this clan because it recognizes the basic amino acid arginine in the P1 pocket. Previous studies carried out with natural amino acids revealed the s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Kasperkiewicz, Paulina, Kołt, Sonia, Janiszewski, Tomasz, Groborz, Katarzyna, Poręba, Marcin, Snipas, Scott J., Salvesen, Guy S., Drąg, Marcin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207715/
https://ncbi.nlm.nih.gov/pubmed/30375474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34476-7
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