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Emerging challenges in the design of selective substrates, inhibitors and activity‐based probes for indistinguishable proteases
Proteases are enzymes that hydrolyze the peptide bond of peptide substrates and proteins. Despite significant progress in recent years, one of the greatest challenges in the design and testing of substrates, inhibitors and activity‐based probes for proteolytic enzymes is achieving specificity toward...
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| Publicado no: | FEBS J |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7164106/ https://ncbi.nlm.nih.gov/pubmed/28052575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14001 |
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