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Design of a Selective Substrate and Activity Based Probe for Human Neutrophil Serine Protease 4

Human neutrophil serine protease 4 (NSP4), also known as PRSS57, is a recently discovered fourth member of the neutrophil serine proteases family. Although its biological function is not precisely defined, it is suggested to regulate neutrophil response and innate immune reactions. To create optimal...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Kasperkiewicz, Paulina, Poreba, Marcin, Snipas, Scott J., Lin, S. Jack, Kirchhofer, Daniel, Salvesen, Guy S., Drag, Marcin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501687/
https://ncbi.nlm.nih.gov/pubmed/26172376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132818
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