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NETosis occurs independently of neutrophil serine proteases

Neutrophils are primary host innate immune cells defending against pathogens. One proposed mechanism by which neutrophils prevent the spread of pathogens is NETosis, the extrusion of cellular DNA resulting in neutrophil extracellular traps (NETs). The protease neutrophil elastase (NE) has been impli...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Kasperkiewicz, Paulina, Hempel, Anne, Janiszewski, Tomasz, Kołt, Sonia, Snipas, Scott J., Drag, Marcin, Salvesen, Guy S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762935/
https://ncbi.nlm.nih.gov/pubmed/33454002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015682
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