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NETosis occurs independently of neutrophil serine proteases

Neutrophils are primary host innate immune cells defending against pathogens. One proposed mechanism by which neutrophils prevent the spread of pathogens is NETosis, the extrusion of cellular DNA resulting in neutrophil extracellular traps (NETs). The protease neutrophil elastase (NE) has been impli...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kasperkiewicz, Paulina, Hempel, Anne, Janiszewski, Tomasz, Kołt, Sonia, Snipas, Scott J., Drag, Marcin, Salvesen, Guy S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762935/
https://ncbi.nlm.nih.gov/pubmed/33454002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015682
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