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NETosis occurs independently of neutrophil serine proteases

Neutrophils are primary host innate immune cells defending against pathogens. One proposed mechanism by which neutrophils prevent the spread of pathogens is NETosis, the extrusion of cellular DNA resulting in neutrophil extracellular traps (NETs). The protease neutrophil elastase (NE) has been impli...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Kasperkiewicz, Paulina, Hempel, Anne, Janiszewski, Tomasz, Kołt, Sonia, Snipas, Scott J., Drag, Marcin, Salvesen, Guy S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762935/
https://ncbi.nlm.nih.gov/pubmed/33454002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015682
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