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NETosis occurs independently of neutrophil serine proteases

Neutrophils are primary host innate immune cells defending against pathogens. One proposed mechanism by which neutrophils prevent the spread of pathogens is NETosis, the extrusion of cellular DNA resulting in neutrophil extracellular traps (NETs). The protease neutrophil elastase (NE) has been impli...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Kasperkiewicz, Paulina, Hempel, Anne, Janiszewski, Tomasz, Kołt, Sonia, Snipas, Scott J., Drag, Marcin, Salvesen, Guy S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762935/
https://ncbi.nlm.nih.gov/pubmed/33454002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015682
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