Emerging principles in protease-based drug discovery

por Drag, Marcin, Salvesen, Guy S.
Publicado 2010

Trojan Horse Strategies Used by Pathogens to Influence the Small Ubiquitin-Like Modifier (SUMO) System of Host Eukaryotic Cells

por Békés, Miklós, Drag, Marcin
Publicado 2012

Chemical Target Validation Studies of Aminopeptidase in Malaria Parasites Using α-Aminoalkylphosphonate and Phosphonopeptide Inhibitors

por Cunningham, Eithne, Drag, Marcin, Kafarski, Pawel, Bell, Angus
Publicado 2008

Caspase Substrates and Inhibitors

por Poręba, Marcin, Stróżyk, Aleksandra, Salvesen, Guy S., Drąg, Marcin
Publicado 2013

Emerging challenges in the design of selective substrates, inhibitors and activity‐based probes for indistinguishable proteases

por Kasperkiewicz, Paulina, Poreba, Marcin, Groborz, Katarzyna, Drag, Marcin
Publicado en FEBS J (2017)

Aminopeptidase Fingerprints, an Integrated Approach for Identification of Good Substrates and Optimal Inhibitors

por Drag, Marcin, Bogyo, Matthew, Ellman, Jonathan A., Salvesen, Guy S.
Publicado 2010

A remarkable activity of human leukotriene A(4) hydrolase (LTA4H) toward unnatural amino acids

por Byzia, Anna, Haeggström, Jesper Z., Salvesen, Guy S., Drag, Marcin
Publicado 2014

Molecular determinants involved in activation of caspase 7

por BOUCHER, Dave, BLAIS, Véronique, DRAG, Marcin, DENAULT, Jean-Bernard
Publicado en Biosci Rep (2011)

Metallo-aminopeptidase inhibitors

por Mucha, Artur, Drag, Marcin, Dalton, John P., Kafarski, Paweł
Publicado en Biochimie (2010)

Gingipain aminopeptidase activities in Porphyromonas gingivalis

por Veillard, Florian, Potempa, Barbara, Poreba, Marcin, Drag, Marcin, Potempa, Jan
Publicado 2012

A toolbox of fluorescent probes for parallel imaging reveals uneven location of serine proteases in neutrophils

por Kasperkiewicz, Paulina, Altman, Yoav, D’Angelo, Maximiliano, Salvesen, Guy S., Drag, Marcin
Publicado en J Am Chem Soc (2017)

Small Molecule Active Site Directed Tools for Studying Human Caspases

por Poreba, Marcin, Szalek, Aleksandra, Kasperkiewicz, Paulina, Rut, Wioletta, Salvesen, Guy S., Drag, Marcin
Publicado en Chem Rev (2015)

Anticancer properties of ester derivatives of betulin in human metastatic melanoma cells (Me-45)

por Drąg-Zalesińska, Małgorzata, Drąg, Marcin, Poręba, Marcin, Borska, Sylwia, Kulbacka, Julita, Saczko, Jolanta
Publicado en Cancer Cell Int (2017)

Comparision of the Cytotoxic Effects of Birch Bark Extract, Betulin and Betulinic Acid Towards Human Gastric Carcinoma and Pancreatic Carcinoma Drug-sensitive and Drug-Resistant Ce...

por Drag, Marcin, Surowiak, Pawel, Drag-Zalesinska, Malgorzata, Dietel, Manfred, Lage, Hermann, Oleksyszyn, Józef
Publicado en Molecules (2009)

Caspase selective reagents for diagnosing apoptotic mechanisms

por Poreba, Marcin, Groborz, Katarzyna, Navarro, Mario, Snipas, Scott J., Drag, Marcin, Salvesen, Guy S.
Publicado en Cell Death Differ (2018)

Leveraging peptide substrate libraries to design inhibitors of bacterial Lon protease

por Babin, Brett M., Kasperkiewicz, Paulina, Janiszewski, Tomasz, Yoo, Euna, Drąg, Marcin, Bogyo, Matthew
Publicado en ACS Chem Biol (2019)

Potent and selective caspase-2 inhibitor prevents MDM-2 cleavage in reversine-treated colon cancer cells

por Poreba, Marcin, Rut, Wioletta, Groborz, Katarzyna, Snipas, Scott J., Salvesen, Guy S., Drag, Marcin
Publicado en Cell Death Differ (2019)

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

por Rut, Wioletta, Zmudzinski, Mikolaj, Snipas, Scott J., Bekes, Miklos, Huang, Tony T., Drag, Marcin
Publicado en Chem Sci (2020)

Synthetic substrates for measuring activity of autophagy proteases: Autophagins (Atg4)

por Shu, Chih-Wen, Drag, Marcin, Bekes, Miklos, Zhai, Dayong, Salvesen, Guy S, Reed, John C
Publicado 2010

An alternative for proteinase K-heat-sensitive protease from fungus Onygena corvina for biotechnology: cloning, engineering, expression, characterization and special application fo...

por Skowron, Piotr M., Krefft, Daria, Brodzik, Robert, Kasperkiewicz, Paulina, Drag, Marcin, Koller, Klaus-Peter
Publicado en Microb Cell Fact (2020)