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Small Molecule Active Site Directed Tools for Studying Human Caspases

Caspases are proteases of clan CD and were described for the first time more than two decades ago. They play critical roles in the control of regulated cell death pathways including apoptosis and inflammation. Due to their involvement in the development of various diseases like cancer, neurodegenera...

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Podrobná bibliografie
Vydáno v:Chem Rev
Hlavní autoři: Poreba, Marcin, Szalek, Aleksandra, Kasperkiewicz, Paulina, Rut, Wioletta, Salvesen, Guy S., Drag, Marcin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610424/
https://ncbi.nlm.nih.gov/pubmed/26551511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrev.5b00434
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