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Small Molecule Active Site Directed Tools for Studying Human Caspases

Caspases are proteases of clan CD and were described for the first time more than two decades ago. They play critical roles in the control of regulated cell death pathways including apoptosis and inflammation. Due to their involvement in the development of various diseases like cancer, neurodegenera...

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Detalhes bibliográficos
Publicado no:Chem Rev
Main Authors: Poreba, Marcin, Szalek, Aleksandra, Kasperkiewicz, Paulina, Rut, Wioletta, Salvesen, Guy S., Drag, Marcin
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610424/
https://ncbi.nlm.nih.gov/pubmed/26551511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrev.5b00434
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