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Small Molecule Active Site Directed Tools for Studying Human Caspases

Caspases are proteases of clan CD and were described for the first time more than two decades ago. They play critical roles in the control of regulated cell death pathways including apoptosis and inflammation. Due to their involvement in the development of various diseases like cancer, neurodegenera...

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Bibliografiske detaljer
Udgivet i:Chem Rev
Main Authors: Poreba, Marcin, Szalek, Aleksandra, Kasperkiewicz, Paulina, Rut, Wioletta, Salvesen, Guy S., Drag, Marcin
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610424/
https://ncbi.nlm.nih.gov/pubmed/26551511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrev.5b00434
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