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Small Molecule Active Site Directed Tools for Studying Human Caspases

Caspases are proteases of clan CD and were described for the first time more than two decades ago. They play critical roles in the control of regulated cell death pathways including apoptosis and inflammation. Due to their involvement in the development of various diseases like cancer, neurodegenera...

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Detalles Bibliográficos
Publicado en:Chem Rev
Autores principales: Poreba, Marcin, Szalek, Aleksandra, Kasperkiewicz, Paulina, Rut, Wioletta, Salvesen, Guy S., Drag, Marcin
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610424/
https://ncbi.nlm.nih.gov/pubmed/26551511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrev.5b00434
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