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Gingipain aminopeptidase activities in Porphyromonas gingivalis

Bestatin, a specific inhibitor of metalloaminopeptidases, inhibits the growth of Porphyromonas gingivalis. To identify its target enzyme, a library of fluorescent substrates was used but no metalloaminopeptidase activity was found. All aminopeptidase activity of P. gingivalis was bestatin-insensitiv...

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Bibliographic Details
Main Authors: Veillard, Florian, Potempa, Barbara, Poreba, Marcin, Drag, Marcin, Potempa, Jan
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180661/
https://ncbi.nlm.nih.gov/pubmed/23667904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/hsz-2012-0222
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