Porphyromonas gingivalis Virulence Factor Gingipain RgpB Shows a Unique Zymogenic Mechanism for Cysteine Peptidases

Zymogenicity is a regulatory mechanism that prevents inadequate catalytic activity in the wrong context. It plays a central role in maintaining microbial virulence factors in an inactive form inside the pathogen until secretion. Among these virulence factors is the cysteine peptidase gingipain B (Rg...

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Autors principals: de Diego, Iñaki, Veillard, Florian T., Guevara, Tibisay, Potempa, Barbara, Sztukowska, Maryta, Potempa, Jan, Gomis-Rüth, F. Xavier
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Enzymology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656285/
https://ncbi.nlm.nih.gov/pubmed/23558682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.444927
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