Intranasal Delivery of Caspase-9 Inhibitor Reduces Caspase-6-Dependent Axon/Neuron Loss and Improves Neurological Function after Stroke

Despite extensive research to develop an effective neuroprotective strategy for the treatment of ischemic stroke, therapeutic options remain limited. Although caspase-dependent death is thought to play a prominent role in neuronal injury, direct evidence of active initiator caspases in stroke and th...

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Detaylı Bibliyografya
Asıl Yazarlar: Akpan, Nsikan, Serrano-Saiz, Esther, Zacharia, Brad E., Otten, Marc L., Ducruet, Andrew F., Snipas, Scott J., Liu, Wen, Velloza, Jennifer, Cohen, Greg, Sosunov, Sergeyi A., Frey, William H., Salvesen, Guy S., Connolly, E. Sander, Troy, Carol M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2011
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Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143191/
https://ncbi.nlm.nih.gov/pubmed/21677173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0698-11.2011
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