Identification of a Minimal Cis-Element and Cognate Trans-factor(s) Required for Induction of Rac2 Gene Expression During K562 Cell Differentiation

Por Muthukrishnan, Rajarajeswari, Skalnik, David G.
Publicado em 2009

CpG Binding Protein Is Crucial for Early Embryonic Development

Por Carlone, Diana L., Skalnik, David G.
Publicado em 2001

Wdr82 Is a C-Terminal Domain-Binding Protein That Recruits the Setd1A Histone H3-Lys4 Methyltransferase Complex to Transcription Start Sites of Transcribed Human Genes

Por Lee, Jeong-Heon, Skalnik, David G.
Publicado em 2008

Rbm15-Mkl1 Interacts with the Setd1b Histone H3-Lys4 Methyltransferase via a SPOC Domain That Is Required for Cytokine-Independent Proliferation

Por Lee, Jeong-Heon, Skalnik, David G.
Publicado em 2012

CXXC Finger Protein 1 Contains Redundant Functional Domains That Support Embryonic Stem Cell Cytosine Methylation, Histone Methylation, and Differentiation

Por Tate, Courtney M., Lee, Jeong-Heon, Skalnik, David G.
Publicado em 2009

CFP1 Interacts with DNMT1 Independently of Association with the Setd1 Histone H3K4 Methyltransferase Complexes

Por Butler, Jill Sergesketter, Lee, Jeong-Heon, Skalnik, David G.
Publicado em 2008

CXXC Finger Protein 1 Restricts the Setd1A Histone H3-Lys4 Methyltransferase Complex to Euchromatin

Por Tate, Courtney M., Lee, Jeong-Heon, Skalnik, David G.
Publicado em 2009

Identification and Characterization of a Novel Human PP1 Phosphatase Complex

Por Lee, Jeong-Heon, You, Jinsam, Dobrota, Erika, Skalnik, David G.
Publicado em 2010

Structural Basis for WDR5 Interaction (Win) Motif Recognition in Human SET1 Family Histone Methyltransferases

Por Dharmarajan, Venkatasubramanian, Lee, Jeong-Heon, Patel, Anamika, Skalnik, David G., Cosgrove, Michael S.
Publicado em 2012

Cloning of a Mammalian Transcriptional Activator That Binds Unmethylated CpG Motifs and Shares a CXXC Domain with DNA Methyltransferase, Human Trithorax, and Methyl-CpG Binding Dom...

Por Shin Voo, Kui, Carlone, Diana L., Jacobsen, Britta M., Flodin, Anna, Skalnik, David G.
Publicado em 2000

Embryonic Stem Cells Lacking the Epigenetic Regulator Cfp1 are Hypersensitive to DNA-Damaging Agents and Exhibit Decreased Ape1/Ref-1 Protein Expression and Endonuclease Activity

Por Tate, Courtney M., Fishel, Melissa L., Holleran, Julianne L., Egorin, Merrill J., Skalnik, David G.
Publicado em 2009

DNA Methyltransferase Protein Synthesis Is Reduced in CXXC Finger Protein 1–Deficient Embryonic Stem Cells

Por Butler, Jill S., Palam, Lakshmi R., Tate, Courtney M., Sanford, Jeremy R., Wek, Ronald C., Skalnik, David G.
Publicado em 2009

Dynamic Loss of H2B Ubiquitylation without Corresponding Changes in H3K4 Trimethylation during Myogenic Differentiation

Por Vethantham, Vasupradha, Yang, Yan, Bowman, Christopher, Asp, Patrik, Lee, Jeong-Heon, Skalnik, David G., Dynlacht, Brian D.
Publicado em 2012

Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltrans...

Por Alicea-Velázquez, Nilda L., Shinsky, Stephen A., Loh, Daniel M., Lee, Jeong-Heon, Skalnik, David G., Cosgrove, Michael S.
Publicado no J Biol Chem (2016)

Cfp1 integrates both CpG content and gene activity for accurate H3K4me3 deposition in embryonic stem cells

Por Clouaire, Thomas, Webb, Shaun, Skene, Pete, Illingworth, Robert, Kerr, Alastair, Andrews, Robert, Lee, Jeong-Heon, Skalnik, David, Bird, Adrian
Publicado em 2012

Reduced Genomic Cytosine Methylation and Defective Cellular Differentiation in Embryonic Stem Cells Lacking CpG Binding Protein

Por Carlone, Diana L., Lee, Jeong-Heon, Young, Suzanne R. L., Dobrota, Erika, Butler, Jill Sergesketter, Ruiz, Joseph, Skalnik, David G.
Publicado em 2005

The Epigenetic Regulator CXXC Finger Protein 1 is Essential for Murine Hematopoiesis

Por Chun, Kristin T., Li, Binghui, Dobrota, Erika, Tate, Courtney, Lee, Jeong-Heon, Khan, Shehnaz, Haneline, Laura, HogenEsch, Harm, Skalnik, David G.
Publicado no PLoS One (2014)

The HIV Protease Inhibitor Ritonavir Inhibits Lung Cancer Cells, in part, by Inhibition of Survivin

Por Srirangam, Anjaiah, Milani, Monica, Mitra, Ranjana, Guo, Zhijun, Rodriguez, Mariangellys, Kathuria, Hitesh, Fukuda, Seiji, Rizzardi, Anthony, Schmechel, Stephen, Skalnik, David G., Pelus, Louis M., Potter, David A.
Publicado em 2011

Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2

Por Higgs, Martin R., Sato, Koichi, Reynolds, John J., Begum, Shabana, Bayley, Rachel, Goula, Amalia, Vernet, Audrey, Paquin, Karissa L., Skalnik, David G., Kobayashi, Wataru, Takata, Minoru, Howlett, Niall G., Kurumizaka, Hitoshi, Kimura, Hiroshi, Stewart, Grant S.
Publicado no Mol Cell (2018)

Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a

Por Kim, Kun-Yong, Tanaka, Yoshiaki, Su, Juan, Cakir, Bilal, Xiang, Yangfei, Patterson, Benjamin, Ding, Junjun, Jung, Yong-Wook, Kim, Ji-Hyun, Hysolli, Eriona, Lee, Haelim, Dajani, Rana, Kim, Jonghwan, Zhong, Mei, Lee, Jeong-Heon, Skalnik, David, Lim, Jeong Mook, Sullivan, Gareth J., Wang, Jianlong, Park, In-Hyun
Publicado no Nat Commun (2018)