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The HIV Protease Inhibitor Ritonavir Inhibits Lung Cancer Cells, in part, by Inhibition of Survivin

INTRODUCTION: Ritonavir is a potential therapeutic agent in lung cancer, but its targets in lung adenocarcinoma are unknown, as are candidate biomarkers for its activity. METHODS: RNAi was used to identify genes whose expression affects ritonavir sensitivity. Synergy between ritonavir, gemcitabine a...

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Détails bibliographiques
Auteurs principaux: Srirangam, Anjaiah, Milani, Monica, Mitra, Ranjana, Guo, Zhijun, Rodriguez, Mariangellys, Kathuria, Hitesh, Fukuda, Seiji, Rizzardi, Anthony, Schmechel, Stephen, Skalnik, David G., Pelus, Louis M., Potter, David A.
Format: Artigo
Langue:Inglês
Publié: 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104055/
https://ncbi.nlm.nih.gov/pubmed/21270666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e31820c9e3c
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