Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a

Embryonic stem cells (ESCs) maintain pluripotency through unique epigenetic states. When ESCs commit to a specific lineage, epigenetic changes in histones and DNA accompany the transition to specialized cell types. Investigating how epigenetic regulation controls lineage specification is critical in...

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Publicado no:Nat Commun
Main Authors: Kim, Kun-Yong, Tanaka, Yoshiaki, Su, Juan, Cakir, Bilal, Xiang, Yangfei, Patterson, Benjamin, Ding, Junjun, Jung, Yong-Wook, Kim, Ji-Hyun, Hysolli, Eriona, Lee, Haelim, Dajani, Rana, Kim, Jonghwan, Zhong, Mei, Lee, Jeong-Heon, Skalnik, David, Lim, Jeong Mook, Sullivan, Gareth J., Wang, Jianlong, Park, In-Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030064/
https://ncbi.nlm.nih.gov/pubmed/29968706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04818-0
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