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The Epigenetic Regulator CXXC Finger Protein 1 is Essential for Murine Hematopoiesis
CXXC finger protein 1 (Cfp1), encoded by the Cxxc1 gene, binds to DNA sequences containing an unmethylated CpG dinucleotide and is an epigenetic regulator of both cytosine and histone methylation. Cxxc1-null mouse embryos fail to gastrulate, and Cxxc1-null embryonic stem cells are viable but cannot...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4254612/ https://ncbi.nlm.nih.gov/pubmed/25470594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113745 |
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